CLNR 324 – Introduction to Biostatistics
Credit: 3 Hours
Statistical methods in health sciences. The course is intended to provide the student with basic knowledge of descriptive statistics, graphing data, probability theory, normal and other common distributions, sampling and estimation, hypothesis testing, ANOVA and other selected statistical methods.
CLNR 442 – Interpersonal Skills
Credit: 2 Hours
Skills such as negotiation, written and verbal communication, managing meetings, facilitation, influencing without authority and assertiveness are often key determinants of success in the workplace. In order to teach students how to be more effective in their careers, students will be coached and evaluated on their ability to plan, conduct and/or facilitate meetings, generate effective communications, and foster effective listening, assertion, and influencing skills. Strategies that are successful during conflictive encounters will be stressed. In addition, students will be exposed to effective techniques used in the selection, mentoring, and management of employees including gender and culture differences.
PHSC 210 – Laboratory Safety
Credit: 1 Hour
An introduction to chemical, physical, and biological hazards associated with laboratory work. Students are introduced to laboratory worker regulations, methods for laboratory and personnel monitoring, and personal protective equipment and clothing. Note: PHSC 210 is a prerequisite (or co-requisite) to all laboratory courses in pharmaceutical sciences.
PHSC 220/220L – Quantitative Laboratory Techniques/Lab
Credit: 2 Hours
An introductory laboratory course concentrating on the basic terminology and mathematical skills needed to perform routine laboratory procedures. Students learn the theory and application of appropriate techniques involved in gravimetric and volumetric analysis. Laboratory skills are honed through a series of exercises culminating in a comprehensive practical examination designed to test the student’s ability to accurately formulate complex biochemical solutions. Prerequisite: CHEM 111/111L, CHEM 113/113L
PHSC 285/285P/285L – Microbiology/Pre-Lab/Lab
Credit: 4 Hours
Microbiology: A Clinical Approach is a course designed to provide undergraduate students with a fundamental understanding of microbes, ranging from molecular processes and information flow to principles of microbial pathogenesis and clinical aspects, with an emphasis on the application of microbiology to the fields of pharmacy and the health sciences. This course will include an introduction to the biology of microorganisms from the perspectives of microbial structure and function, metabolism, genetics, and diversity. The clinical significance of microbial biology will be emphasized throughout the course. Laboratory exercises are designed to mirror didactic subjects and give students hands-on experience with microbial organisms.
PHSC 290 Seminar – Introduction to Pharmaceutical Sciences
Credit: 1.0 hour
This course provides an introductory overview that defines Pharmaceutical Sciences, providing context for how earlier courses are interwoven with advanced material to provide a superior skill set for students interested primarily in development of quality medicines.
PHSC 323 – General Biochemistry
Credit: 3 hours
A comprehensive course in biochemistry which presents protein, lipid and nucleic acid biosynthesis and catabolism. Principles of enzyme kinetics, regulation, energy metabolism, signal transduction and macromolecular structure-function relationships are presented. It is recommended that a student take Microbiology or Cell Biology before taking this course. Prerequisite: CHEM 227/227L and CHEM 228/228L Co-requisite: PHSC 325/325L
PHSC 324 – Introduction to Biostatistics
Credit: 3 Hours
Statistical methods in health sciences. The course is intended to provide the student with basic knowledge of descriptive statistics, graphing data, probability theory, normal and other common distributions, sampling and estimation, hypothesis testing, ANOVA and other selected statistical methods.
PHSC 325/325L – General Biochemistry Pre-Lab/Lab
Credit: 1 hour
This course is intended to provide the student with the experience of working with basic techniques used in the study of biomolecules, particularly proteins. Students will gain knowledge of protein characterization techniques, such as gel filtration, enzyme kinetics, PAGE, ELISA. A detailed laboratory notebook will be used to document all lab work, and its contents will assist with the written reports. At end of the semester, lab practical is given as well. Students must attend a weekly pre-lab session. Co-requisite PHSC 323
PHSC 326 – Molecular Biology
Credit: 3 hours
Molecular biology: a practical approach. This course is intended to provide the students with an understanding of the tools and techniques used in molecular biology, especially as they apply to the research and pharmaceutical application of modern recombinant DNA technology. The focus will be on the analysis and manipulation of genes and gene products. Both theoretical and practical aspects will be covered. This course provides an introduction to the basic concepts of recombinant DNA technology, such as cloning of genes from DNA libraries; use of various organisms for expression of gene products; analysis of DNA; and enzymatic modifications of DNA. Application of these techniques will be illustrated by use of homework problems as well as an associated laboratory course. Prerequisite: PHSC 325/325L
PHSC 327/327L – Molecular Biology Pre-lab/Lab
Credit: 1 hour
This course is intended to provide the student with experience in working with basic techniques used in the construction and manipulation of recombinant DNA molecules. Emphasis will be placed on explaining laboratory results in terms of fundamental concepts in molecular biology. A detailed laboratory notebook will be used to document all lab work. This course is open to all majors, but priority will be given to Pharma-cortical Sciences majors. Prerequisites: Biochemistry with lab and Microbiology with lab or instructor’s permission. Co-requisite: PHSC 326
PHSC 328 – Introduction to Pharmacology
Credit: 4 Hours
The basic principles of drug action are covered through discussion of the responses of biological systems to drugs and chemicals. Emphasis is placed on understanding mechanism of action through detailed exploration of receptor-mediated events (pharmacodynamics). The course considers the quantification of drug action as well as the absorption, distribution, metabolism, and elimination of xenobiotics (pharmacokinetics) and how these and other factors relate to drug action, and surveys all of the major classes of drugs.
Prerequisite: BIOL 221/221L and CHEM227/227L
PHSC 336 – Scientific Literature Seminar
Credit: 1 Hour
Students are introduced to literature searching and critical analysis techniques in this series of courses. The courses promote the formulation of critical thinking approaches. Special emphasis is placed on communication techniques. Students apply their knowledge and skill in the form of written and oral presentations developed by researching the current pharmaceutical and biomedical literature. Prerequisite: PHSC 451.
PHSC 338 – Product & Process Validation
Credit: 2 Hours
This course introduces students to the principles of good manufacturing practices (cGMP), quality control and quality assurance. The basics of regulatory compliance, the global nature of regulations and the importance of validation in the Pharmaceutical and Biotechnology Industries are discussed. Students learn about the validation of facilities, equipment, utilities, cleaning procedures, computer systems, assays and processes. The course also illustrates the importance of the team approach to validation and the need for thorough documentation of all associated activities.
PHSC 340 – Pharmaceutical Biotechnology of Natural Products Study Abroad
Credit: 4 hours
This course includes a pre-departure seminar component (1.0 credit hour) in the Fall semester and a December travel/laboratory component (3.0 credit hours) in Chile. The course will enable students to conduct fieldwork in diverse natural environments in Chile and explore the potential medicinal properties of natural products through an international laboratory experience at the Universidad de La Frontera in Temuco, Chile. Students will gain intercultural under-standing and collaboration, increase their awareness of critical issues in global health, develop relevant skills in becoming a more effective and knowledgeable citizen of the world, and engage in effective teamwork among members of the group.
PHSC 404 – Research in Pharmaceutical Sciences
Credit: Variable (Maximum 3 Hours)
The purpose of this elective course is to introduce pharmaceutical sciences students to methods of basic science and/or clinical research. This involves application of the scientific processes of hypothesis formation, literature evaluation, experimental design, development of technical skills, data acquisition and analysis, and formal presentation of results. Requires permission of instructor.
PHSC 410 – Analytical Instrumentation
Credit: 3 hours
This is a comprehensive introductory course that provides students with an in-depth study of the theory and operation of scientific instrumentation typically found in pharmaceutical, chemical, and biotechnical research and analytical facilities. The following analytical techniques will be covered: ultraviolet/visible, atomic absorption/emission, infrared, and fluorescence spectrophotometry; gas chromatography, high performance liquid chromatography, and sample preparation. The students will learn how to follow guidelines for analysis of various chemicals and dosage forms in the US Pharmacopeia. Prerequisite: PHSC 220/220L Co-requisite: PHSC 411/411L
PHSC 411/411L – Analytical Instrumentation Pre-Lab/Lab
Credit: 1 hour
This course is intended to provide the student with the experience working with basic techniques used in pharmaceutical, chemical, and biotechnical research and analytical facilities. Students will gain knowledge of spectroscopic and chromatographic instrumentation, plus working with the US Pharmacopeia. A detailed laboratory notebook will be used to document all lab work and its contents will assist with the written reports. Students must attend a weekly pre-lab session. Co-requisite: PHSC 410
PHSC 418 – Industrial Pharmacy
Credit: 3 hours
This survey course introduces students to common pharmaceutical dosage forms, pre-formulation and formulation design, and selected concepts in pharmaceutics and biopharmaceutics.
Prerequisites: Enrollees should have completed Laboratory Safety, Quantitative Laboratory Techniques (PHSC220/220L) and Analytical Instrumentation (PHSC410/411). Concurrent enrollment in Industrial Pharmacy Pre-Lab (PHSC 419) and Industrial Pharmacy Lab (PHSC 419L) is also required. Enrollment is limited to students who have declared Pharmaceutical Science as a major or permission of the course director.
PHSC 419/419L – Industrial Pharmacy Pre-Lab/Lab
Credit: 1 hour
This laboratory course is designed to prepare and analyze several pharmaceutical dosage forms under Current Good Manufacturing Practices (CGMP-like) environment and conduct pre-formulation relevant experiments to determine pKa, pH-solubility, and stability kinetics.
PHSC 438 – Pharmaceutical Methodology& Bioprocessing
Credit: 3 hours
The course will emphasize analysis of active pharmaceutical ingredients, excipients, and products; process design, analysis and purification of bio-macromolecules by means of modern techniques. Pharmaceutical Methodologies includes but not limited to validation of analytical methods, theory and Interpretation of Mass Spectrometry spectra. Bioprocessing covers the proper treatments (isolation, purification, and modification) of compounds or bio-products for analysis, use of large-scale cell culture for pharmaceutical production, and theoretical considerations for purification of cell-produced pharmaceuticals. Students will learn basic troubleshoot techniques that can be applied as they proceed into the workplace. Co-requisite: PHSC 439L
PHSC 439L – Pharmaceutical Methodology& Bioprocessing Lab
Credit: 1 hour
This course is intended to provide the student with the experience working with basic techniques used in the analysis of active pharmaceutical ingredients, excipients, and products; process design, analysis and purification of bio-macromolecules by means of modern techniques. Student will experience HPLC method optimization, Mass Spectrometry, determining optimized cell growth curves, theoretically modeled purification of cell-produced pharmaceuticals. A detailed laboratory notebook will be used to document all lab work and its contents will assist with the written reports. Students will put into practice basic trouble shooting techniques. Co-requisite: PHSC 438
PHSC 442 – Interpersonal Skills
Credit: 2 Hours
Skills such as negotiation, written and verbal communication, managing meetings, facilitation, influencing without authority and assertiveness are often key determinants of success in the workplace. In order to teach students how to be more effective in their careers, students will be coached and evaluated on their ability to plan, conduct and/or facilitate meetings, generate effective communications, and foster effective listening, assertion, and influencing skills. Strategies that are successful during conflictive encounters will be stressed. In addition, students will be exposed to effective techniques used in the selection, mentoring, and management of employees including gender and culture differences.
PHSC 451 – Scientific & Technical Writing
Credit: 1.5 Hours
Scientific and Technical Writing is a required course for Pharmaceutical Sciences and Clinical Research majors designed to enable students to effectively and accurately write and review a variety of technical documents used in pharmaceutical-related industries. Prerequisite: ENGL 101 and 102.
PHSC 490 – Senior Experiential Capstone
Credit: 13.0 Hours
The internship provides practical experience in the pharmaceutical, chemical or biotechnology industries. Students and participating in industrial facilities are matched to provide comprehensive work experience. Students present an overview of the companies in which they worked and provide a synopsis of their roles/experiences in the organizations during their internship.